Aston Villa defender Axel Tuanzebe is ineligible to face his parent club so Kortney Hause will start if head coach Dean Smith persists with a back three. John McGinn has overcome concussion but Leon Bailey is out until mid-October with a thigh strain and Morgan Sanson will be sidelined for a month. The midfielder, who made a first appearance since April against Chelsea in the Carabao Cup on Wednesday, suffered a hamstring injury during that tie.
Manchester United are still not quite right for me. They are going to win a load of games this season, but there will be times where they unexpectedly come unstuck.
The big question for me is can United win without playing well? I know they won at West Ham last week, but they got away with that one really. Then they changed their whole team when they lost to the same opposition in the Carabao Cup in midweek, but so did the Hammers.
Aston Villa beat Everton comfortably last time out and, before that, they showed against Chelsea how they can make life difficult for the top sides. United should still win this one but it might not be straightforward.
A spectacular finish at the London Stadium last weekend saw Jesse Lingard put Man United 2-1 ahead before West Ham United captain Mark Noble had a penalty saved by David de Gea, and the 20-time English champions will now be looking to secure their third straight Premier League victory this weekend.
The Red Devils have two huge home games before the international break, as they will welcome Villarreal to Old Trafford in the Champions League next Wednesday, and there is certainly pressure on the team following their disappointing result against Young Boys in the middle of the month.
Cristiano Ronaldo was again on the scoresheet against West Ham in the league last weekend, and the Portugal international has now netted four times in three appearances since returning to Old Trafford.
Villa, meanwhile, have had a mixed start to the 2021-22 Premier League season, winning two, drawing one and losing two of their five matches to collect seven points, which has left them in 10th spot in the table.
Like Man United, Dean Smith’s side were also knocked out of the EFL Cup on Wednesday night, with the club losing on penalties at Stamford Bridge after playing out a 1-1 draw with Chelsea.
Villa also lost 3-0 at Chelsea in the Premier League on September 11 but were in impressive form against Everton in the league last weekend, recording a 3-0 victory, with Matty Cash and Leon Bailey on the scoresheet for the hosts, who now have two tough away games against Man United and Tottenham Hotspur.
Smith’s team, who finished 11th in the Premier League last season, will certainly believe that they are capable of harming Man United this weekend, but Villa have incredibly picked up just one win in their last 45 Premier League games against Man United, losing 33 times in the process.
What’s more, the Red Devils have won 18 of their last 21 home league games against Villa, who are without a success over Man United in any competition since a 1-0 victory at Old Trafford in December 2009.
Man United will again be without the services of Marcus Rashford and Amad Diallo on Saturday through injury, but Edinson Cavani will be involved, having now returned to first-team training following a knock.
Solskjaer is expected to make 11 changes from the EFL Cup defeat to West Ham, and it would not be a surprise to see the same side that took to the field for the league game against the Hammers last weekend.
Indeed, Paul Pogba should operate off the left, with Scott McTominay and Fred in midfield, while Mason Greenwood and Bruno Fernandes will feature in the areas behind Ronaldo.
Jadon Sancho has found it difficult to make his mark in the early stages of his career at Old Trafford, and the England international is expected to start on the bench against Smith’s side.